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Anti-Inflammatory Terpenes in Cannabis—Which Ones Are the Most Effective?

Posted by Daniel Gordon on

Whether you suffer from anxiety, nausea, pain or insomnia, terpenes can help. True Blue sells Cannalope Haze terpenes, for example, which have therapeutic qualities believed to alleviate chronic pain and migraines. You can also buy SFV OG terpenes which may mitigate stress. It’s also true that, owing to the entourage effect, terpenes act as a supplement to CBD and THC, boosting their effects.

Our focus today is on anti-inflammatory terpenes in marijuana. More than 200 different terpenes have been identified in the cannabis plant, and while research in this area has a long way to go, recent studies indicate that some of the major cannabis terpenes have the potential to successfully treat inflammation.


The impact of inflammation

Inflammation of the Leg

Inflammation, the human body’s natural response to infection and injury, is something we all have experience with. Common symptoms include pain, fatigue, fever and rash.

Typically, inflammation lasts for a few hours to a few days. This is called acute inflammation. When it lasts for a longer period of time—months or even years—it’s known as chronic inflammation.

Along with causing physical discomfort, chronic inflammation can permanently damage healthy tissue. This in turn increases your risk of cancer, heart disease, diabetes and other serious health conditions. Therefore, managing and treating inflammation is extremely important.


Using terpenes for inflammation

Terpenes are better understood by the general public now than they were ten years ago, or even a couple years ago. Still, we tend to sell them short by placing so much emphasis on their aromatic properties.

In case you weren’t already aware, weed smells and tastes the way it does thanks to its unique combination of terpenes. But that’s only half the story: beyond imparting aromas and flavors, these organic hydrocarbons have significant positive effects on our health.

When it comes to using cannabis terpenes for inflammation, a number of them are proven to be beneficial.

Several studies have identified beta-caryophyllene (BCP) as an anti-inflammatory agent. One of them, published in the Journal of Science of Food and Agriculture in 2019, concluded that BCP had “anti‐inflammatory activity against two different models of acute inflammation and infection.” Aside from cannabis, BCP is present in hops, cloves, rosemary and basil, among many other herbs.


Linalool is a terpene common to a lot of cannabis strains. It’s also the primary component of many essential oils, which are commonly used to help manage inflammation. According to a 2002 study, linalool is a likely anti-inflammatory agent.

A 2017 study demonstrated that limonene, abundant in citrus fruits as well as cannabis, has notable anti-inflammatory properties. In the study, rats with ulcerative colitis (an inflammatory disease of the bowels) were treated with limonene. The researchers found that damage resulting from the disease was “significantly reduced by the anti‑inflammatory effects of limonene.”

Myrcene Terpene Icon

Myrcene, the most highly concentrated terpene in cannabis, is yet another proven anti-inflammatory agent. In 2015, the European Journal of Pharmacology published a paper showing that myrcene “has significant anti-inflammatory and anti-catabolic effects” and could potentially treat osteoarthritis.

The list of anti-inflammatory terpenes in marijuana will likely expand as research progresses.

 Read more: Myrcene - The Mother of All Terpenes


What about CBD?

CBD oil for inflammation

Numerous studies have demonstrated the anti-inflammatory powers of cannabinoids. Because it’s well-tolerated, has minimal side effects, and doesn’t make you high, CBD has become a very popular choice for individuals seeking relief from inflammation, not to mention a host of other ailments.

A 2018 article published in Cannabis and Cannabinoid Research states that, while terpenes can be successful in reducing acute inflammation, CBD appears to be better for chronic inflammation.

So, what if you add terpenes to CBD? Will doing so enhance CBD’s anti-inflammatory properties? Research suggests that the answer is yes.

Specifically, an article in the British Journal of Pharmacology showed that CBD is even better at treating inflammation when it’s integrated with terpenes. According to the authors, this entourage effect also applies to the treatment of conditions like anxiety, depression, chronic pain, epilepsy, and bacterial infections.

If these scientific studies have piqued your interest - why not buy your terpenes online with us and see what happens?

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